Endocrine Abstracts

A 78-year-old female presented with acute onset of severe headache and vomiting. Sub arachnoid haemorrhage was suspected but a CT brain scan was ‘normal’ and CSF bilirubin absent.Three months later she complained of lethargy and a thyroid function test suggested secondary hypothyroidism. Further investigations confirmed partial hypopituitarism (growth hormone preserved) and review of the previous CT scan suggested the presence of a pituitary ma...

The association between Cushing's syndrome and pregnancy is uncommon due to associated sub-fertility. Recognising this is important, as there implications for both mother and foetus.A twenty year old presented at twenty three weeks gestation. Insulin requiring diabetes had developed as had oedema. Pigmented abdominal striae were prominent. Her serum sodium concentration was noted to be low (3 mmol/l). 24 hour urinary free cortisol was elevated (>1380 ...